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Exercise from La La Land

In an eye-opening demonstration of nature's ingenuity, researchers at Princeton University recently discovered that exercise creates vibrant new brain cells -- and then shuts them down when they shouldn't be in action.

For some time, scientists studying exercise have been puzzled by physical activity's two seemingly incompatible effects on the brain. On the one hand, exercise is known to prompt the creation of new and very excitable brain cells. At the same time, exercise can induce an overall pattern of calm in certain parts of the brain.

Elizabeth Gould, director of the Gould Lab at Princeton, who wrote the paper with her graduate student Timothy Schoenfeld, now at the National Institute of Mental Health, and others, "is that the hippocampus of runners is vastly different from that of sedentary animals. Not only are there more excitatory neurons and more excitatory synapses, but the inhibitory neurons are more likely to become activated, presumably to dampen the excitatory neurons, in response to stress." The findings were published in The Journal of Neuroscience


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